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Silencing the Tlr4 Gene Alleviates Methamphetamine-Induced Hepatotoxicity by Inhibiting Lipopolysaccharide-Mediated Inflammation in Mice

Methamphetamine (METH) is a stimulant drug. METH abuse induces hepatotoxicity, although the mechanisms are not well understood. METH-induced hepatotoxicity was regulated by TLR4-mediated inflammation in BALB/c mice in our previous study. To further investigate the underlying mechanisms, the wild-typ...

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Detalles Bibliográficos
Autores principales: Wang, Li-Bin, Chen, Li-Jian, Wang, Qi, Xie, Xiao-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224410/
https://www.ncbi.nlm.nih.gov/pubmed/35743253
http://dx.doi.org/10.3390/ijms23126810