Design and Synthesis of Menthol and Thymol Derived Ciprofloxacin: Influence of Structural Modifications on the Antibacterial Activity and Anticancer Properties

Sixteen new Ciprofloxacin derivatives were designed and successfully synthesized. In an in silico experiment, lipophilicity was established for obtained compounds. All compounds were screened for antimicrobial activity using standard and clinical strains. As for Gram-positive hospital microorganisms...

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Detalles Bibliográficos
Autores principales: Szostek, Tomasz, Szulczyk, Daniel, Szymańska-Majchrzak, Jolanta, Koliński, Michał, Kmiecik, Sebastian, Otto-Ślusarczyk, Dagmara, Zawodnik, Aleksandra, Rajkowska, Eliza, Chaniewicz, Kinga, Struga, Marta, Roszkowski, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224473/
https://www.ncbi.nlm.nih.gov/pubmed/35743043
http://dx.doi.org/10.3390/ijms23126600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224473/
https://www.ncbi.nlm.nih.gov/pubmed/35743043
http://dx.doi.org/10.3390/ijms23126600

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