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Orchestrated Action of AMPK Activation and Combined VEGF/PD-1 Blockade with Lipid Metabolic Tunning as Multi-Target Therapeutics against Ovarian Cancers

Ovarian cancer is one of the most lethal gynecological malignancies worldwide, and chemoresistance is a critical obstacle in the clinical management of the disease. Recent studies have suggested that exploiting cancer cell metabolism by applying AMP-activated protein kinase (AMPK)-activating agents...

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Detalles Bibliográficos
Autores principales: Yung, Mingo M. H., Siu, Michelle K. Y., Ngan, Hextan Y. S., Chan, David W., Chan, Karen K. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224484/
https://www.ncbi.nlm.nih.gov/pubmed/35743298
http://dx.doi.org/10.3390/ijms23126857