Evaluation of Hydroxyl Radical Reactivity by Thioether Group Proximity in Model Peptide Backbone: Methionine versus S-Methyl-Cysteine

Hydroxyl radicals (HO(•)) have long been regarded as a major source of cellular damage. The reaction of HO(•) with methionine residues (Met) in peptides and proteins is a complex multistep process. Although the reaction mechanism has been intensively studied, some essential parts remain unsolved. In...

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Detalles Bibliográficos
Autores principales: Chatgilialoglu, Chryssostomos, Grzelak, Magdalena, Skotnicki, Konrad, Filipiak, Piotr, Kazmierczak, Franciszek, Hug, Gordon L., Bobrowski, Krzysztof, Marciniak, Bronislaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224496/
https://www.ncbi.nlm.nih.gov/pubmed/35742994
http://dx.doi.org/10.3390/ijms23126550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224496/
https://www.ncbi.nlm.nih.gov/pubmed/35742994
http://dx.doi.org/10.3390/ijms23126550

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