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Maternal and Fetal Bile Acid Homeostasis Regulated by Sulfated Progesterone Metabolites through FXR Signaling Pathway in a Pregnant Sow Model

Abnormally elevated circulating bile acids (BA) during pregnancy endanger fetal survival and offspring health; however, the pathology and underlying mechanisms are poorly understood. A total of nineteen pregnant sows were randomly assigned to day 60 of gestation, day 90 of gestation (G60, G90), and...

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Detalles Bibliográficos
Autores principales: Wang, Peng, Yuan, Peiqiang, Lin, Sen, Zhong, Heju, Zhang, Xiaoling, Zhuo, Yong, Li, Jian, Che, Lianqiang, Feng, Bin, Lin, Yan, Xu, Shengyu, Wu, De, Burrin, Douglas G, Fang, Zhengfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224516/
https://www.ncbi.nlm.nih.gov/pubmed/35742938
http://dx.doi.org/10.3390/ijms23126496