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Control of STING Agonistic/Antagonistic Activity Using Amine-Skeleton-Based c-di-GMP Analogues

Stimulator of Interferon Genes (STING) is a type of endoplasmic reticulum (ER)-membrane receptor. STING is activated by a ligand binding, which leads to an enhancement of the immune-system response. Therefore, a STING ligand can be used to regulate the immune system in therapeutic strategies. Howeve...

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Detalles Bibliográficos
Autores principales: Yanase, Yuta, Tsuji, Genichiro, Nakamura, Miki, Shibata, Norihito, Demizu, Yosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224868/
https://www.ncbi.nlm.nih.gov/pubmed/35743289
http://dx.doi.org/10.3390/ijms23126847