A Case Report of Immunotherapy-Resistant MSI-H Gastric Cancer with Significant Intrapatient Tumoral Heterogeneity Characterized by Histologic Dedifferentiation

We describe a patient with both gastric adenocarcinoma and metastatic squamous cell carcinoma (SCC) of unknown primary site. The possibility of a single malignant clonal process as opposed to differing primaries was supported by the finding of both histologies exhibiting high microsatellite instabil...

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Detalles Bibliográficos
Autores principales: Kethireddy, Nikhila, Arvanitis, Leonidas, LoBello, Janine, Woo, Yanghee, Szelinger, Szabolcs, Chao, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224875/
https://www.ncbi.nlm.nih.gov/pubmed/35743482
http://dx.doi.org/10.3390/jcm11123413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224875/
https://www.ncbi.nlm.nih.gov/pubmed/35743482
http://dx.doi.org/10.3390/jcm11123413

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