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The orphan ligand, activin C, signals through activin receptor-like kinase 7

Activin ligands are formed from two disulfide-linked inhibin β (Inhβ) subunit chains. They exist as homodimeric proteins, as in the case of activin A (ActA; InhβA/InhβA) or activin C (ActC; InhβC/InhβC), or as heterodimers, as with activin AC (ActAC; InhβA:InhβC). While the biological functions of A...

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Detalles Bibliográficos
Autores principales: Goebel, Erich J, Ongaro, Luisina, Kappes, Emily C, Vestal, Kylie, Belcheva, Elitza, Castonguay, Roselyne, Kumar, Ravindra, Bernard, Daniel J, Thompson, Thomas B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224996/
https://www.ncbi.nlm.nih.gov/pubmed/35736809
http://dx.doi.org/10.7554/eLife.78197