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Model Informed Precision Dosing Tool Forecasts Trough Infliximab and Associates with Disease Status and Tumor Necrosis Factor-Alpha Levels of Inflammatory Bowel Diseases

Background: Substantial inter-and intra-individual variability of Infliximab (IFX) pharmacokinetics necessitates tailored dosing approaches. Here, we evaluated the performances of a Model Informed Precision Dosing (MIPD) Tool in forecasting trough Infliximab (IFX) levels in association with disease...

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Detalles Bibliográficos
Autores principales: Primas, Christian, Reinisch, Walter, Panetta, John C., Eser, Alexander, Mould, Diane R., Dervieux, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225059/
https://www.ncbi.nlm.nih.gov/pubmed/35743387
http://dx.doi.org/10.3390/jcm11123316