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Diterpenoid Caesalmin C Delays Aβ-Induced Paralysis Symptoms via the DAF-16 Pathway in Caenorhabditis elegans

Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease in the world. However, there is no effective drug to cure it. Caesalmin C is a cassane-type diterpenoid abundant in Caesalpinia bonduc (Linn.) Roxb. In this study, we investigated the effect of caesalmin C on Aβ-induced toxicit...

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Detalles Bibliográficos
Autores principales: Zhang, Zong-Ping, Bai, Xue, Cui, Wen-Bo, Chen, Xiao-Han, Liu, Xu, Zhi, De-Juan, Zhang, Zhan-Xin, Fei, Dong-Qing, Wang, Dong-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225120/
https://www.ncbi.nlm.nih.gov/pubmed/35743309
http://dx.doi.org/10.3390/ijms23126871