Chemical Genetic Validation of CSNK2 Substrates Using an Inhibitor-Resistant Mutant in Combination with Triple SILAC Quantitative Phosphoproteomics

Casein Kinase 2 (CSNK2) is an extremely pleiotropic, ubiquitously expressed protein kinase involved in the regulation of numerous key biological processes. Mapping the CSNK2-dependent phosphoproteome is necessary for better characterization of its fundamental role in cellular signalling. While ATP-c...

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Detalles Bibliográficos
Autores principales: Gyenis, Laszlo, Menyhart, Daniel, Cruise, Edward S., Jurcic, Kristina, Roffey, Scott E., Chai, Darren B., Trifoi, Flaviu, Fess, Sam R., Desormeaux, Paul J., Núñez de Villavicencio Díaz, Teresa, Rabalski, Adam J., Zukowski, Stephanie A., Turowec, Jacob P., Pittock, Paula, Lajoie, Gilles, Litchfield, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225150/
https://www.ncbi.nlm.nih.gov/pubmed/35755813
http://dx.doi.org/10.3389/fmolb.2022.909711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225150/
https://www.ncbi.nlm.nih.gov/pubmed/35755813
http://dx.doi.org/10.3389/fmolb.2022.909711

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