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Development of disulfide-stabilized Fabs for targeting of antibody-directed nanotherapeutics
Antibody-directed nanotherapeutics (ADNs) represent a promising delivery platform for selective delivery of an encapsulated drug payload to the site of disease that improves the therapeutic index. Although both single-chain Fv (scFv) and Fab antibody fragments have been used for targeting, no platfo...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225506/ https://www.ncbi.nlm.nih.gov/pubmed/35708974 http://dx.doi.org/10.1080/19420862.2022.2083466 |