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A perspective toward mass spectrometry-based de novo sequencing of endogenous antibodies

A key step in therapeutic and endogenous humoral antibody characterization is identifying the amino acid sequence. So far, this task has been mainly tackled through sequencing of B-cell receptor (BCR) repertoires at the nucleotide level. Mass spectrometry (MS) has emerged as an alternative tool for...

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Detalles Bibliográficos
Autores principales: de Graaf, Sebastiaan C., Hoek, Max, Tamara, Sem, Heck, Albert J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225641/
https://www.ncbi.nlm.nih.gov/pubmed/35699511
http://dx.doi.org/10.1080/19420862.2022.2079449