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How Is CYP17A1 Activity Altered in Autism? A Pilot Study to Identify Potential Pharmacological Targets

Background: Increasing evidence exists that higher levels of androgens can be found in individuals with autism. Evidence yields to a susceptible role of Cytochrome P450 17A1 (CYP17A1) with its catalyzation of the two distinct types of substrate oxidation by a hydroxylase activity (17-alpha hydroxyla...

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Detalles Bibliográficos
Autores principales: Gasser, Benedikt Andreas, Kurz, Johann, Dick, Bernhard, Mohaupt, Markus Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225657/
https://www.ncbi.nlm.nih.gov/pubmed/35743898
http://dx.doi.org/10.3390/life12060867