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Antigenic landscapes on Staphylococcus aureus pore-forming toxins reveal insights into specificity and cross-neutralization

Staphylococcus aureus carries an exceptional repertoire of virulence factors that aid in immune evasion. Previous single-target approaches for S. aureus-specific vaccines and monoclonal antibodies (mAbs) have failed in clinical trials due to the multitude of virulence factors released during infecti...

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Detalles Bibliográficos
Autores principales: Kailasan, Shweta, Kant, Ravi, Noonan-Shueh, Madeleine, Kanipakala, Tulasikumari, Liao, Grant, Shulenin, Sergey, Leung, Daisy W., Alm, Richard A., Adhikari, Rajan P., Amarasinghe, Gaya K., Gross, Michael L., Aman, M. Javad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225675/
https://www.ncbi.nlm.nih.gov/pubmed/35730685
http://dx.doi.org/10.1080/19420862.2022.2083467