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Substantial involvement of TRPM7 inhibition in the therapeutic effect of Ophiocordyceps sinensis on pulmonary hypertension

Ophiocordyceps sinensis (OCS), an entomopathogenic fungus, is known to exert antiproliferative and antitissue remodeling effects. Vascular remodeling and vasoconstriction play critical roles in the development of pulmonary hypertension (PH). The therapeutic potential of OCS for PH was investigated u...

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Detalles Bibliográficos
Autores principales: HIRAISHI, KEIZO, KURAHARA, LIN HAI, FENG, JIANLIN, YAMAMURA, AYA, CUI, YUANYUAN, YAHIRO, EIJI, YOKOMISE, HIROYASU, GO, TETSUHIKO, ISHIKAWA, KAORI, YOKOTA, NAOYA, FUJIWARA, ATSUSHI, ONITSUKA, MIKI, ABE, KOHTARO, OHGA, SHOJI, SATOH, TORU, OKADA, YASUMASA, YUE, LIXIA, INOUE, RYUJI, HIRANO, KATSUYA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225677/
https://www.ncbi.nlm.nih.gov/pubmed/33691194
http://dx.doi.org/10.1016/j.trsl.2021.03.004