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PROTACs for BRDs proteins in cancer therapy: a review

BRDs proteins that recognise chromatin acetylation regulate gene expression, are epigenetic readers and master transcription coactivators. BRDs proteins are now emerging as targets for new therapeutic development. Blocking the function of any of BRDs proteins can be a control agent for diseases, suc...

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Detalles Bibliográficos
Autores principales: Wang, Chao, Zhang, Yujing, Yang, Shanbo, Chen, Wujun, Xing, Dongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225710/
https://www.ncbi.nlm.nih.gov/pubmed/35702740
http://dx.doi.org/10.1080/14756366.2022.2081164