Proteolysis-targeting chimaeras (PROTACs) as pharmacological tools and therapeutic agents: advances and future challenges

Proteolysis-targeting chimaeras (PROTACs) have been developed to be an emerging technology for targeted protein degradation and attracted the favour of academic institutions, large pharmaceutical enterprises, and biotechnology companies. The mechanism is based on the inhibition of protein function b...

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Detalles Bibliográficos
Autores principales: Wang, Chao, Zhang, Yujing, Zhang, Tingting, Shi, Lingyu, Geng, Zhongmin, Xing, Dongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225776/
https://www.ncbi.nlm.nih.gov/pubmed/35702041
http://dx.doi.org/10.1080/14756366.2022.2076675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225776/
https://www.ncbi.nlm.nih.gov/pubmed/35702041
http://dx.doi.org/10.1080/14756366.2022.2076675

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