SLC7A11/GPX4 Inactivation-Mediated Ferroptosis Contributes to the Pathogenesis of Triptolide-Induced Cardiotoxicity

Triptolide exhibits promising efficacy in various cancers and immune diseases while its clinical application has been strongly restricted by its severe side effects, especially cardiotoxicity. However, the underlying mechanism of triptolide-induced cardiotoxicity (TIC) remains unclear. The RNA-seq a...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Xian, Chen, Cheng, Han, Dong, Zhou, Wei, Cui, Yaowen, Tang, Xianglin, Xiao, Chengrong, Wang, Yuguang, Gao, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225845/
https://www.ncbi.nlm.nih.gov/pubmed/35757509
http://dx.doi.org/10.1155/2022/3192607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225845/
https://www.ncbi.nlm.nih.gov/pubmed/35757509
http://dx.doi.org/10.1155/2022/3192607

Ejemplares similares