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Vericiguat Modulates Osteoclast Differentiation and Bone Resorption via a Balance between VASP and NF-κB Pathways

Bone homeostasis has been a dynamic equilibrium between osteoclasts (OCs) and osteoblasts (OBs). However, excessive activation of OCs could disturb the bone homeostasis. As a result, effective medical interventions for patients are greatly demanding. NO/guanylate cyclase (GC)/cGMP signaling cascade...

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Detalles Bibliográficos
Autores principales: Sun, Kaiqiang, Kong, Fanqi, Lin, Feng, Li, Fudong, Sun, Jingchuan, Ren, Changzhen, Zheng, Bing, Shi, Jiangang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225892/
https://www.ncbi.nlm.nih.gov/pubmed/35757109
http://dx.doi.org/10.1155/2022/1625290