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A two-step search and run response to gradients shapes leukocyte navigation in vivo

Migrating cells must interpret chemical gradients to guide themselves within tissues. A long-held principle is that gradients guide cells via reorientation of leading-edge protrusions. However, recent evidence indicates that protrusions can be dispensable for locomotion in some contexts, raising que...

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Detalles Bibliográficos
Autores principales: Georgantzoglou, Antonios, Poplimont, Hugo, Walker, Hazel A., Lämmermann, Tim, Sarris, Milka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225946/
https://www.ncbi.nlm.nih.gov/pubmed/35731205
http://dx.doi.org/10.1083/jcb.202103207