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Deletions on 9p21 are associated with worse outcomes after anti-PD-1/PD-L1 monotherapy but not chemoimmunotherapy

NCCN guidelines for first-line treatment of advanced non-squamous non-small-cell lung cancer (NSCLC) patients without targetable driver alterations includes either immunotherapy alone or in combination with chemotherapy. In this study, we investigated genomic predictors of survival after immunothera...

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Detalles Bibliográficos
Autores principales: Ebot, Ericka M., Duncan, Daniel L., Tolba, Khaled, Fabrizio, David, Frampton, Garrett M., Comment, Leah A., Albacker, Lee A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225995/
https://www.ncbi.nlm.nih.gov/pubmed/35739333
http://dx.doi.org/10.1038/s41698-022-00286-4