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Towards a general approach for tailoring the hydrophobic binding site of phenylalanine ammonia-lyases

Unnatural substituted amino acids play an important role as chiral building blocks, especially for pharmaceutical industry, where the synthesis of chiral biologically active molecules still represents an open challenge. Recently, modification of the hydrophobic binding pocket of phenylalanine ammoni...

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Detalles Bibliográficos
Autores principales: Tork, Souad Diana, Moisă, Mădălina Elena, Cserepes, Lilla, Filip, Alina, Nagy, Levente Csaba, Irimie, Florin Dan, Bencze, László Csaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226071/
https://www.ncbi.nlm.nih.gov/pubmed/35739148
http://dx.doi.org/10.1038/s41598-022-14585-0