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Towards a general approach for tailoring the hydrophobic binding site of phenylalanine ammonia-lyases
Unnatural substituted amino acids play an important role as chiral building blocks, especially for pharmaceutical industry, where the synthesis of chiral biologically active molecules still represents an open challenge. Recently, modification of the hydrophobic binding pocket of phenylalanine ammoni...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226071/ https://www.ncbi.nlm.nih.gov/pubmed/35739148 http://dx.doi.org/10.1038/s41598-022-14585-0 |