Coiled-coil heterodimer-based recruitment of an exonuclease to CRISPR/Cas for enhanced gene editing

The CRISPR/Cas system has emerged as a powerful and versatile genome engineering tool, revolutionizing biological and biomedical sciences, where an improvement of efficiency could have a strong impact. Here we present a strategy to enhance gene editing based on the concerted action of Cas9 and an ex...

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Detalles Bibliográficos
Autores principales: Lainšček, Duško, Forstnerič, Vida, Mikolič, Veronika, Malenšek, Špela, Pečan, Peter, Benčina, Mojca, Sever, Matjaž, Podgornik, Helena, Jerala, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226073/
https://www.ncbi.nlm.nih.gov/pubmed/35739111
http://dx.doi.org/10.1038/s41467-022-31386-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226073/
https://www.ncbi.nlm.nih.gov/pubmed/35739111
http://dx.doi.org/10.1038/s41467-022-31386-1

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