Fibrillin-1 mutant mouse captures defining features of human primary open glaucoma including anomalous aqueous humor TGF beta-2

Primary open angle glaucoma (POAG) features an optic neuropathy, elevated aqueous humor (AH) TGFβ2, and major risk factors of central corneal thickness (CCT), increasing age and intraocular pressure (IOP). We examined Tight skin (Tsk) mice to see if mutation of fibrillin-1, a repository for latent T...

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Detalles Bibliográficos
Autores principales: Ko, MinHee K., Woo, Jeong-Im, Gonzalez, Jose M., Kim, Gayeoun, Sakai, Lynn, Peti-Peterdi, Janos, Kelber, Jonathan A., Hong, Young-Kwon, Tan, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226129/
https://www.ncbi.nlm.nih.gov/pubmed/35739142
http://dx.doi.org/10.1038/s41598-022-14062-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226129/
https://www.ncbi.nlm.nih.gov/pubmed/35739142
http://dx.doi.org/10.1038/s41598-022-14062-8

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