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Intravenous immunoglobulin induces IgG internalization by tolerogenic myeloid dendritic cells that secrete IL-10 and expand Fc-specific regulatory T cells

Intravenous immunoglobulin (IVIG) is used as an immunomodulatory agent in many inflammatory conditions including Multisystem Inflammatory Syndrome-Children (MIS-C) and Kawasaki disease (KD). However, the exact mechanisms underlying its anti-inflammatory action are incompletely characterized. Here, w...

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Detalles Bibliográficos
Autores principales: Hsieh, Li-En, Song, Jaeyoon, Tremoulet, Adriana H, Burns, Jane C, Franco, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226148/
https://www.ncbi.nlm.nih.gov/pubmed/35536993
http://dx.doi.org/10.1093/cei/uxac046