Asparagine synthetase regulates lung-cancer metastasis by stabilizing the β-catenin complex and modulating mitochondrial response

The availability of asparagine is the limitation of cell growth and metastasis. Asparagine synthetase (ASNS) was an essential enzyme for endogenous asparagine products. In our study, ASNS-induced asparagine products were essential to maintain tumor growth and colony formations in vitro. But mutated...

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Detalles Bibliográficos
Autores principales: Cai, Dong-Jing, Zhang, Zi-Yu, Bu, Yue, Li, Li, Deng, Yue-Zhen, Sun, Lun-Quan, Hu, Cheng-Ping, Li, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226154/
https://www.ncbi.nlm.nih.gov/pubmed/35739087
http://dx.doi.org/10.1038/s41419-022-05015-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226154/
https://www.ncbi.nlm.nih.gov/pubmed/35739087
http://dx.doi.org/10.1038/s41419-022-05015-0

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