An epitope-optimized human H3N2 influenza vaccine induces broadly protective immunity in mice and ferrets

There is a crucial need for an improved H3N2 influenza virus vaccine due to low vaccine efficacy rates and increased morbidity and mortality associated with H3N2-dominated influenza seasons. Here, we utilize a computational design strategy to produce epitope-optimized, broadly cross-reactive H3 hema...

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Detalles Bibliográficos
Autores principales: Bullard, Brianna L., DeBeauchamp, Jennifer, Pekarek, Matthew J., Petro-Turnquist, Erika, Vogel, Peter, Webby, Richard J., Weaver, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226166/
https://www.ncbi.nlm.nih.gov/pubmed/35739199
http://dx.doi.org/10.1038/s41541-022-00492-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226166/
https://www.ncbi.nlm.nih.gov/pubmed/35739199
http://dx.doi.org/10.1038/s41541-022-00492-y

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