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An epitope-optimized human H3N2 influenza vaccine induces broadly protective immunity in mice and ferrets
There is a crucial need for an improved H3N2 influenza virus vaccine due to low vaccine efficacy rates and increased morbidity and mortality associated with H3N2-dominated influenza seasons. Here, we utilize a computational design strategy to produce epitope-optimized, broadly cross-reactive H3 hema...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226166/ https://www.ncbi.nlm.nih.gov/pubmed/35739199 http://dx.doi.org/10.1038/s41541-022-00492-y |