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Chimeric adenoviral (Ad5.F35) and listeria vector prime-boost immunization is safe and effective for cancer immunotherapy

Strategies to augment immunity to self/neoantigens expressed by cancers are urgently needed to expand the proportion of patients benefiting from immunotherapy, particularly for GI cancers where only a fraction of patients respond to immunotherapies. However, current vaccine strategies are limited by...

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Detalles Bibliográficos
Autores principales: Flickinger, John C., Staudt, Ross E., Singh, Jagmohan, Carlson, Robert D., Barton, Joshua R., Baybutt, Trevor R., Rappaport, Jeffrey A., Zalewski, Alicja, Pattison, Amanda, Waldman, Scott A., Snook, Adam E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226178/
https://www.ncbi.nlm.nih.gov/pubmed/35739202
http://dx.doi.org/10.1038/s41541-022-00483-z