A mathematical model of GLUT1 modulation in rods and RPE and its differential impact in cell metabolism

We present a mathematical model of key glucose metabolic pathways in two cells of the human retina: the rods and the retinal pigmented epithelium (RPE). Computational simulations of glucose transporter 1 (GLUT1) inhibition in the model accurately reproduce experimental data from conditional knockout...

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Detalles Bibliográficos
Autores principales: Aparicio, Andrea, Camacho, Erika T., Philp, Nancy J., Wirkus, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226191/
https://www.ncbi.nlm.nih.gov/pubmed/35739198
http://dx.doi.org/10.1038/s41598-022-13950-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226191/
https://www.ncbi.nlm.nih.gov/pubmed/35739198
http://dx.doi.org/10.1038/s41598-022-13950-3

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