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A mathematical model of GLUT1 modulation in rods and RPE and its differential impact in cell metabolism
We present a mathematical model of key glucose metabolic pathways in two cells of the human retina: the rods and the retinal pigmented epithelium (RPE). Computational simulations of glucose transporter 1 (GLUT1) inhibition in the model accurately reproduce experimental data from conditional knockout...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226191/ https://www.ncbi.nlm.nih.gov/pubmed/35739198 http://dx.doi.org/10.1038/s41598-022-13950-3 |