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AlphaFold2 models indicate that protein sequence determines both structure and dynamics

AlphaFold 2 (AF2) has placed Molecular Biology in a new era where we can visualize, analyze and interpret the structures and functions of all proteins solely from their primary sequences. We performed AF2 structure predictions for various protein systems, including globular proteins, a multi-domain...

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Detalles Bibliográficos
Autores principales: Guo, Hao-Bo, Perminov, Alexander, Bekele, Selemon, Kedziora, Gary, Farajollahi, Sanaz, Varaljay, Vanessa, Hinkle, Kevin, Molinero, Valeria, Meister, Konrad, Hung, Chia, Dennis, Patrick, Kelley-Loughnane, Nancy, Berry, Rajiv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226352/
https://www.ncbi.nlm.nih.gov/pubmed/35739160
http://dx.doi.org/10.1038/s41598-022-14382-9