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DNA replication is highly resilient and persistent under the challenge of mild replication stress
Mitotic DNA synthesis (MiDAS) has been proposed to restart DNA synthesis during mitosis because of replication fork stalling in late interphase caused by mild replication stress (RS). Contrary to this proposal, we find that cells exposed to mild RS in fact maintain continued DNA replication througho...
Autores principales: | Mocanu, Camelia, Karanika, Eleftheria, Fernández-Casañas, María, Herbert, Alex, Olukoga, Tomisin, Özgürses, Mete Emir, Chan, Kok-Lung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226383/ https://www.ncbi.nlm.nih.gov/pubmed/35443178 http://dx.doi.org/10.1016/j.celrep.2022.110701 |
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