Heparanase Is a Putative Mediator of Endothelial Glycocalyx Damage in COVID-19 – A Proof-of-Concept Study

Coronavirus disease 2019 (COVID-19) is a systemic disease associated with injury (thinning) of the endothelial glycocalyx (eGC), a protective layer on the vascular endothelium. The aim of this translational study was to investigate the role of the eGC-degrading enzyme heparanase (HPSE), which is kno...

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Detalles Bibliográficos
Autores principales: Drost, Carolin Christina, Rovas, Alexandros, Osiaevi, Irina, Rauen, Matthias, van der Vlag, Johan, Buijsers, Baranca, Salmenov, Rustem, Lukasz, Alexander, Pavenstädt, Hermann, Linke, Wolfgang A., Kümpers, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226442/
https://www.ncbi.nlm.nih.gov/pubmed/35757776
http://dx.doi.org/10.3389/fimmu.2022.916512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226442/
https://www.ncbi.nlm.nih.gov/pubmed/35757776
http://dx.doi.org/10.3389/fimmu.2022.916512

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