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Strong Selectional Forces Fine-Tune CpG Content in Genes Involved in Neurological Disorders as Revealed by Codon Usage Patterns

Neurodegenerative disorders cause irreversible damage to the neurons and adversely affect the quality of life. Protein misfolding and their aggregation in specific parts of the brain, mitochondrial dysfunction, calcium load, proteolytic stress, and oxidative stress are among the causes of neurodegen...

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Detalles Bibliográficos
Autores principales: Khandia, Rekha, Sharma, Anushri, Alqahtani, Taha, Alqahtani, Ali M., Asiri, Yahya I., Alqahtani, Saud, Alharbi, Ahmed M., Kamal, Mohammad Amjad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226491/
https://www.ncbi.nlm.nih.gov/pubmed/35757545
http://dx.doi.org/10.3389/fnins.2022.887929