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ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia

ARMC5 is implicated in several pathological conditions, but its function remains unknown. We have previously identified CUL3 and RPB1 (the largest subunit of RNA polymerase II (Pol II) as potential ARMC5-interacting proteins. Here, we show that ARMC5, CUL3 and RBX1 form an active E3 ligase complex s...

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Detalles Bibliográficos
Autores principales: Lao, Linjiang, Bourdeau, Isabelle, Gagliardi, Lucia, He, Xiao, Shi, Wei, Hao, Bingbing, Tan, Minjia, Hu, Yan, Peng, Junzheng, Coulombe, Benoit, Torpy, David J, Scott, Hamish S, Lacroix, Andre, Luo, Hongyu, Wu, Jiangping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226510/
https://www.ncbi.nlm.nih.gov/pubmed/35687106
http://dx.doi.org/10.1093/nar/gkac483