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Tissue-specific regulation of translational readthrough tunes functions of the traffic jam transcription factor

Translational readthrough (TR) occurs when the ribosome decodes a stop codon as a sense codon, resulting in two protein isoforms synthesized from the same mRNA. TR has been identified in several eukaryotic organisms; however, its biological significance and mechanism remain unclear. Here, we quantif...

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Detalles Bibliográficos
Autores principales: Karki, Prajwal, Carney, Travis D, Maracci, Cristina, Yatsenko, Andriy S, Shcherbata, Halyna R, Rodnina, Marina V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226519/
https://www.ncbi.nlm.nih.gov/pubmed/34897510
http://dx.doi.org/10.1093/nar/gkab1189