Insight into RNA–DNA primer length counting by human primosome

The human primosome, a four-subunit complex of primase and DNA polymerase alpha (Polα), synthesizes chimeric RNA–DNA primers of a limited length for DNA polymerases delta and epsilon to initiate DNA replication on both chromosome strands. Despite recent structural insights into the action of its two...

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Detalles Bibliográficos
Autores principales: Baranovskiy, Andrey G, Lisova, Alisa E, Morstadt, Lucia M, Babayeva, Nigar D, Tahirov, Tahir H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226528/
https://www.ncbi.nlm.nih.gov/pubmed/35689638
http://dx.doi.org/10.1093/nar/gkac492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226528/
https://www.ncbi.nlm.nih.gov/pubmed/35689638
http://dx.doi.org/10.1093/nar/gkac492

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