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CRISPR/Cas9-mediated genome editing reveals 12 testis-enriched genes dispensable for male fertility in mice

Gene expression analyses suggest that more than 1000–2000 genes are expressed predominantly in mouse and human testes. Although functional analyses of hundreds of these genes have been performed, there are still many testis-enriched genes whose functions remain unexplored. Analyzing gene function us...

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Detalles Bibliográficos
Autores principales: Oyama, Yuki, Miyata, Haruhiko, Shimada, Keisuke, Fujihara, Yoshitaka, Tokuhiro, Keizo, Garcia, Thomas X, Matzuk, Martin M, Ikawa, Masahito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226692/
https://www.ncbi.nlm.nih.gov/pubmed/34290169
http://dx.doi.org/10.4103/aja.aja_63_21