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Positive rate‐dependent action potential prolongation by modulating potassium ion channels

Pharmacological agents that prolong action potential duration (APD) to a larger extent at slow rates than at the fast excitation rates typical of ventricular tachycardia exhibit reverse rate dependence. Reverse rate dependence has been linked to the lack of efficacy of class III agents at preventing...

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Detalles Bibliográficos
Autor principal: Cabo, Candido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226816/
https://www.ncbi.nlm.nih.gov/pubmed/35748083
http://dx.doi.org/10.14814/phy2.15356