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Positive rate‐dependent action potential prolongation by modulating potassium ion channels
Pharmacological agents that prolong action potential duration (APD) to a larger extent at slow rates than at the fast excitation rates typical of ventricular tachycardia exhibit reverse rate dependence. Reverse rate dependence has been linked to the lack of efficacy of class III agents at preventing...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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John Wiley and Sons Inc.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226816/ https://www.ncbi.nlm.nih.gov/pubmed/35748083 http://dx.doi.org/10.14814/phy2.15356 |