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Accum™ Technology: A Novel Conjugable Primer for Onco-Immunotherapy

Compromised activity is a common impediment for biologics requiring endosome trafficking into target cells. In cancer cells, antibody-drug conjugates (ADCs) are trapped in endosomes or subsequently pumped extracellularly, leading to a reduction in intracellular accumulation. In subsets of dendritic...

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Detalles Bibliográficos
Autores principales: El-Kadiry, Abed El-Hakim, Beaudoin, Simon, Plouffe, Sebastien, Rafei, Moutih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227040/
https://www.ncbi.nlm.nih.gov/pubmed/35744930
http://dx.doi.org/10.3390/molecules27123807