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Accum™ Technology: A Novel Conjugable Primer for Onco-Immunotherapy
Compromised activity is a common impediment for biologics requiring endosome trafficking into target cells. In cancer cells, antibody-drug conjugates (ADCs) are trapped in endosomes or subsequently pumped extracellularly, leading to a reduction in intracellular accumulation. In subsets of dendritic...
Autores principales: | El-Kadiry, Abed El-Hakim, Beaudoin, Simon, Plouffe, Sebastien, Rafei, Moutih |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227040/ https://www.ncbi.nlm.nih.gov/pubmed/35744930 http://dx.doi.org/10.3390/molecules27123807 |
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