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A New Live Auxotrophic Vaccine Induces Cross-Protection against Klebsiella pneumoniae Infections in Mice

The development of a whole-cell vaccine from bacteria auxotrophic for D-amino acids present in the bacterial cell wall is considered a promising strategy for providing protection against bacterial infections. Here, we constructed a prototype vaccine, consisting of a glutamate racemase-deficient muta...

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Detalles Bibliográficos
Autores principales: Moscoso, Miriam, Vallejo, Juan A., Cabral, Maria P., García, Patricia, Fuentes-Valverde, Víctor, Gato, Eva, Arca-Suárez, Jorge, Aja-Macaya, Pablo, Bou, Germán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227041/
https://www.ncbi.nlm.nih.gov/pubmed/35746561
http://dx.doi.org/10.3390/vaccines10060953