Exorbitant Drug Loading of Metformin and Sitagliptin in Mucoadhesive Buccal Tablet: In Vitro and In Vivo Characterization in Healthy Volunteers

The aim of the proposed study is to develop a mucoadhesive buccal delivery system for the sustained delivery of metformin (MET) and sitagliptin (SIT) against diabetes mellitus (DM) with improved bioavailability. Polymeric blend of Carbopol(®) 940 (CP), agarose (AG) or polyvinylpyrrolidone K30 (PVP)...

Descripción completa

Detalles Bibliográficos
Autores principales: Shakir, Rouheena, Hanif, Sana, Salawi, Ahmad, Arshad, Rabia, Sarfraz, Rai Muhammad, Irfan, Muhammad, Raza, Syed Atif, Barkat, Kashif, Sabei, Fahad Y., Almoshari, Yosif, Alshamrani, Meshal, Syed, Muhammad Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227047/
https://www.ncbi.nlm.nih.gov/pubmed/35745605
http://dx.doi.org/10.3390/ph15060686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227047/
https://www.ncbi.nlm.nih.gov/pubmed/35745605
http://dx.doi.org/10.3390/ph15060686

Ejemplares similares