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Exorbitant Drug Loading of Metformin and Sitagliptin in Mucoadhesive Buccal Tablet: In Vitro and In Vivo Characterization in Healthy Volunteers

The aim of the proposed study is to develop a mucoadhesive buccal delivery system for the sustained delivery of metformin (MET) and sitagliptin (SIT) against diabetes mellitus (DM) with improved bioavailability. Polymeric blend of Carbopol(®) 940 (CP), agarose (AG) or polyvinylpyrrolidone K30 (PVP)...

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Detalles Bibliográficos
Autores principales:	Shakir, Rouheena, Hanif, Sana, Salawi, Ahmad, Arshad, Rabia, Sarfraz, Rai Muhammad, Irfan, Muhammad, Raza, Syed Atif, Barkat, Kashif, Sabei, Fahad Y., Almoshari, Yosif, Alshamrani, Meshal, Syed, Muhammad Ali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227047/ https://www.ncbi.nlm.nih.gov/pubmed/35745605 http://dx.doi.org/10.3390/ph15060686

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