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Prediction Models for Brain Distribution of Drugs Based on Biomimetic Chromatographic Data

The development of high-throughput approaches for the valid estimation of brain disposition is of great importance in the early drug screening of drug candidates. However, the complexity of brain tissue, which is protected by a unique vasculature formation called the blood–brain barrier (BBB), compl...

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Detalles Bibliográficos
Autores principales: Vallianatou, Theodosia, Tsopelas, Fotios, Tsantili-Kakoulidou, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227077/
https://www.ncbi.nlm.nih.gov/pubmed/35744794
http://dx.doi.org/10.3390/molecules27123668