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Prediction Models for Brain Distribution of Drugs Based on Biomimetic Chromatographic Data
The development of high-throughput approaches for the valid estimation of brain disposition is of great importance in the early drug screening of drug candidates. However, the complexity of brain tissue, which is protected by a unique vasculature formation called the blood–brain barrier (BBB), compl...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227077/ https://www.ncbi.nlm.nih.gov/pubmed/35744794 http://dx.doi.org/10.3390/molecules27123668 |