TP-CSO: A Triptolide Prodrug for Pancreatic Cancer Treatment

Triptolide (TP) is a potential drug candidate for the treatment of cancer, but its use was hampered by its systemic toxicity and poor water solubility. Hence, a TP-CSO prodrug was synthesized by conjugating TP to chitosan oligosaccharide (CSO), and characterized by (1)H NMR, FTIR, DSC and XRD analys...

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Detalles Bibliográficos
Autores principales: Wang, Xinlong, Zeng, Huahui, Zhu, Xin, Xu, Duanjie, Tian, Qikang, Wang, Can, Zhao, Lingzhou, Zhao, Junwei, Miao, Mingsan, Wu, Xiangxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227231/
https://www.ncbi.nlm.nih.gov/pubmed/35744811
http://dx.doi.org/10.3390/molecules27123686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227231/
https://www.ncbi.nlm.nih.gov/pubmed/35744811
http://dx.doi.org/10.3390/molecules27123686

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