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TP-CSO: A Triptolide Prodrug for Pancreatic Cancer Treatment
Triptolide (TP) is a potential drug candidate for the treatment of cancer, but its use was hampered by its systemic toxicity and poor water solubility. Hence, a TP-CSO prodrug was synthesized by conjugating TP to chitosan oligosaccharide (CSO), and characterized by (1)H NMR, FTIR, DSC and XRD analys...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227231/ https://www.ncbi.nlm.nih.gov/pubmed/35744811 http://dx.doi.org/10.3390/molecules27123686 |