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Bromodomain and Extra-Terminal Protein Inhibitors: Biologic Insights and Therapeutic Potential in Pediatric Brain Tumors

Pediatric brain tumors have surpassed leukemia as the leading cause of cancer-related death in children. Several landmark studies from the last two decades have shown that many pediatric brain tumors are driven by epigenetic dysregulation within specific developmental contexts. One of the major dete...

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Detalles Bibliográficos
Autores principales: Groves, Andrew, Clymer, Jessica, Filbin, Mariella G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227239/
https://www.ncbi.nlm.nih.gov/pubmed/35745584
http://dx.doi.org/10.3390/ph15060665